'Painkiller' on Netflix cast and characters (2024)

Netflix is shining a spotlight on one of the biggest culprits behind the opioid crisis through its latest limited series, Painkiller.

The six-episode series debuted on the streaming platform on Aug. 10 and quickly caught viewer attention. Its focus on, in particular, Purdue Pharma’s contributions to the opioid scourge is sparking widespread debate, as people revisit a conversation that’s been simmering for decades. Purdue Pharma is one of the biggest, and most insidious culprits behind the rise of opioids around the nation, and the manufacturer’s focus on OxyContin, in particular, led to a crisis, particularly in the United States. Deaths from prescription opioids have dropped slightly in recent years, as a result of better access to information and the slow downfall of Purdue Pharma.

The company’s been embroiled in legal disputes for more than a decade now, and — despite several high-dollar payouts — its still paying the price for the human cost of its pursuit of wealth. Netflix’s work to shine a light on the company, and people, behind the painkiller craze isn’t enough to ease the hurt Purdue caused — but it is reminding people of how much work is yet to be done.

The Painkiller cast

Painkiller seeks to tell a multifaceted story about the rise of the opioid epidemic and the company that’s been paying for its involvement since the 2000s. It highlights a number of important figures over the course of its 6-episode limited run, including the executives and salesmen behind OxyContin’s development.

The Sacklers

'Painkiller' on Netflix cast and characters (1)

The Sackler family is at the core of the drama that unfolds across Painkiller. The family purchased Purdue Pharma from its founders in 1952, and, in the early 90s, pivoted it to primarily focus on pain management. Soon, drugs like fentanyl, codeine, and OxyContin were the company’s bread and butter —and, within a few years, a wave of opioid-related deaths were the result of their efforts —as was their silence on the drugs’ addictive properties.

Matthew Broderick leads the Sackler squad as Richard Sackler, one of the family’s primary forces in pumping out highly addictive painkillers. Joining him as Raymond Sackler and Mortimer Sackler are Sam Anderson (as Raymond) and John Rothman (as Mortimer).

Edie Flowers

'Painkiller' on Netflix cast and characters (2)

A vital element of the Painkiller story is brought to audiences by the talented Uzo Aduba, who plays Edie Flowers, a lawyer with the US attorney’s Roanoke, VA. office. Flowers is an amalgamation of several different real-world figures, who — while not entirely fictional — were altered and dramatized into one character to help keep the story tight. She is one of the driving forces of the Painkiller plot, as she works to develop a case against Purdue Pharma and its contributions to the opioid crisis.

Dr. Gregory Fitzgibbons

'Painkiller' on Netflix cast and characters (3)

Like Flowers, Dr. Gregory Fitzgibbons isn’t entirely based on a real-life person. Instead, he is based on a collection of doctors who, following the rise of OxyContin, refused to prescribe it to their patients, despite pressure from the likes of Richard Sackler. He’s played, in Painkiller, by John Ales, who audiences will recognize from his stints on Euphoria, Star Trek: Picard, and Station 19.

The Krygers

'Painkiller' on Netflix cast and characters (4)

The drama that compounds over the course of Painkiller is very much based on real life, but the series hesitates to put OxyContin’s real-life victims in the spotlight. Instead, it creates new, fictional characters, who experience fallout based on real-world experiences. The Krygers — Glen, Lily, and Tyler — aren’t based on any specific IRL people, but their tragic experience very much is. The family is played by Taylor Kitsch, of John Carter and The Terminal List fame, who portrays Glen, alongside Carolina Bartczak’s Lily and Jack Mulhern’s Tyler.

Additional cast

'Painkiller' on Netflix cast and characters (5)

The Painkiller cast isn’t massive, but quite a few talented people came together to bring this story to life. Joining heavy hitters like Matthew Broderick are Tyler Ritter, who plays John Brownlee, Ron Lea, who brings Bill Havens to life, Ana Cruz Kayneas Brianna Ortiz, West Duchovny as Shannon Schaeffer, John Murphy, who adds Michael Friedman into the mix, and Dina Shihabi, who plays a character simply classified as “Britt.”

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'Painkiller' on Netflix cast and characters (2024)

FAQs

Is Painkiller on Netflix a true story? ›

While Painkiller is a fictionalized depiction of the birth of the opioid crisis, it refers to many real events and figures, including the Sackler family. Sadly, Painkiller only scratches the surface of the damage that opioid abuse has caused.

Who is the star of the Painkiller on Netflix? ›

The causes and consequences of America's opioid epidemic unfold in this drama following its perpetrators, victims and an investigator seeking the truth. Watch all you want. Matthew Broderick, Uzo Aduba and Taylor Kitsch star in this provocative drama based on real events.

Who is the woman in Painkiller? ›

One such character is federal investigator Edie Flowers (Uzo Aduba). Following her breakout roles in Orange Is the New Black and HBO's In Treatment reboot, Aduba's character in Painkiller is determined to hold the Sacklers accountable.

Where was Netflix Painkiller filmed? ›

Filmed in Toronto, ON

Toronto's vibrant and exhilarating entertainment venues - within the city's core and along Lake Ontario - made them an ideal filming location for this provocative drama.

Where is Richard Sackler now? ›

Since 2013, he has lived outside Austin, Texas.

Was there a whistleblower at Purdue Pharma? ›

Steven May started at Purdue Pharma as a sales rep in 1999, and years later went on to allege fraud against Purdue as a participant in a whistle-blower lawsuit (which was dismissed on procedural grounds).

Is OxyContin still available? ›

Oxycodone is only available on prescription. It comes as slow-release tablets, standard tablets and capsules, and a liquid that you swallow.

Is OxyContin still legal? ›

OxyContin, a trade name for the narcotic oxycodone hydrochloride, is a painkiller available in the United States only by prescription.

Is Edie Flowers a real person? ›

“The world of Edie Flowers, who is a fictitious person — but is a composite of a number of investigators, runs alongside the very real Richard Sackler. Having those points of intersection where the two worlds come together was incredibly impactful and powerful.”

Is the family in Painkiller real? ›

While the vast majority of the limited series draws directly from historical events, most of its main characters—Edie, Glen, Shannon, and Britt—are fictional, although the people they stand for are certainly not. Each episode begins with a real person reading a disclaimer: “This program is based on real events.

Is Purdue Pharma still in business? ›

As of August, 2023, Purdue Pharma remains in chapter 11 bankruptcy, pending a Department of Justice appeal to the United States Supreme Court, of a 2nd U.S. Circuit Court Of Appeals ruling that the bankruptcy proceedings may continue.

Who owns the mansion in Painkiller? ›

More from Robb Report

On camera, the massive spread portrayed the real-life residence once owned by the billionaire Purdue Pharma chairman and president Richard Sackler, portrayed by Matthew Broderick. It also was featured in season three of the Amazon Prime superhero series The Boys.

How many episodes of Painkiller are on Netflix? ›

What is the Painkiller documentary on Netflix? ›

Painkiller, a fictionalized telling of the origins and aftermath of the opioid crisis in America. The causes and consequences of America's opioid epidemic unfold in this drama following its perpetrators, victims and an investigator seeking the truth.

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